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They can discuss the situation with you and provide medical advice.

These defects can begin in the first month, even before you know you are pregnant.

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Acetazolamide, isoniazid, buspirone, carbamazepine, glutethimide, ondansetron, and levetiracetam have been reported to be useful in some, but not all, studies.

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Use of valproate during pregnancy increases the risk for neural tube defects and other malformations.

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Studies have found that individuals who take anticonvulsant medications including valproate have suicidal thoughts or behaviors up to 2 times more often than individuals who take placebo (inactive medication).

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We did not include any information that was not published in primary literature form so any “Data on File” with Abbott Laboratories that is not published is not included in this review.

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Divalproex (also known as valproate or valproic acid) is a prescription medication used to treat seizures and manic episodes in people with bipolar disorder and to prevent migraines.

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Furthermore, while group cognitive behavior therapy alone reduced the depression scores, this effect was not significantly greater than the effect of the placebo.

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These figures vary substantially with age: migraines most commonly start between 15 and 24 years of age and occur most frequently in those 35 to 45 years of age.

In that case, you should increase as slowly as every 4 to even every 7 days (there is probably not much benefit in going any slower than that).

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Valproate poses a higher risk for serious birth defects than many other AEDs and should be avoided, if possible, during the first trimester.

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Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013.

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Marital discord can cause sexual dysfunction, but nearly 25% of patients believe that the lack of sexual fulfillment has contributed to marital problems.

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Elevated reward-related neural activation as a unique biological marker of bipolar disorder: Assessment and treatment implications.

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This was a 12-month, Phase 3, open-label extension of a 3-month, double-blind, placebo-controlled, multicenter study of adolescents aged 12 to 17 years with migraine headaches who had either completed the previous study or had discontinued because of lack of efficacy.

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In patients with asymptomatic elevations, closely monitor plasma ammonia concentrations and, if elevations persist, consider discontinuance of the drug.

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Our study was designed to determine whether adjunctive antidepressant therapy reduces symptoms of bipolar depression without increasing the risk of mania.

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This older group of patients should be closely monitored during treatment with divalproex sodium delayed-release capsules for the development of acute liver injury with regular clinical assessments and serum liver test monitoring.

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Amitriptyline is probably effective in migraine prevention and is probably as effective as topiramate and possibly as effective as venlafaxine in the prevention of migraines.

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